Cooking pork tenderloin can vary depending on the method you choose. Generally, roasting it in the oven at 375°F takes about 25-30 minutes, or until it reaches an internal temperature of 145°F. Let it rest for a few minutes before slicing to keep it juicy. Do you prefer cooking pork in the oven, or are you thinking of trying another method like grilling? How did your interest in cooking pork tenderloin come about?