Protecting cells in Excel can help maintain data integrity by preventing unwanted changes. You can do this by first selecting the cells you want to keep unprotected and right-clicking to select 'Format Cells,' then unchecking 'Locked.' Afterward, go to 'Review' and click 'Protect Sheet,' enabling you to set a password. Do you often manage sensitive or important data in Excel? Any particular challenges you've faced with Excel that we can look into together?